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The dosage is based on your medical condition and response to treatmentTo reduce your risk of side effectsyour doctor may direct you to start this medication at a low dose and gradually increase your doseFollow your doctor’s instructions carefullyTake this medication regularly to get the most benefit from itTo help you remembertake it at the same time each day.

Taking MAO inhibitors with his medication may cause a seriouspossibly fataldrug interactionAvoid taking MAO inhibitorsisocarboxazidlinezolidmethylene bluemoclobemidephenelzineprocarbazinerasagilinesafinamideselegilinetranylcypromineduring treatment with this medicationMost MAO inhibitors should also not be taken for 2 weeks before and at least 5 weeks after treatment with this medicationAsk your doctor when to start or stop taking this medication.

Patients should be advised of the signs and symptoms associated with serotonin syndrome that may include mental status changesfor exampleagitationhallucinationsdeliriumand comaautonomic instabilityfor exampletachycardialabile blood pressuredizzinessdiaphoresisflushinghyperthermianeuromuscular changesfor exampletremorrigiditymyoclonushyperreflexiaincoordinationseizuresand/or gastrointestinal symptomsfor examplenauseavomitingdiarrheaPatients should be cautioned to seek medical care immediately if they experience these symptoms.

Excreted in milkavoidAAP states effect on nursing infants is unknown but may be of concern)

Tell your doctor right away if any of these unlikely but serious side effects occurunusual or severe mental/mood changessuch as agitationunusual high energy/excitementthoughts of suicideeasy bruising/bleedingmuscle weakness/spasmshakinesstremordecreased interest in sexchanges in sexual abilityunusual weight loss.

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