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Caution is indicated in the coadministration of tricyclic antidepressants tcas with paroxetine hydrochloride, because paroxetine may inhibit tca metabolism.

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CUse with caution if benefits outweigh risksAnimal studies show risk and human studies not available or neither animal nor human studies done.

Controlled-release tabletsInitial dose12.5 mg orally once a day Maintenance dose12.5 to 37.5 mg orally once a day.

Paroxetine may also be used for purposes not listed in this medication guide.

Paroxetine is used to treat depressionpanic attacksanxiety disordersand a severe form of premenstrual syndromepremenstrual dysphoric disorderIt works by helping to restore the balance of a certain natural substanceserotoninin the brain.

Some young people have thoughts about suicide when first taking an antidepressantStay alert to changes in your mood or symptomsReport any new or worsening symptoms to your doctor.

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