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SMA is a genetic neurodegenerative disease that involves impairment of the neuromuscular transmissionSo Mestinonwhich facilitates the nerve signal transmission at the neuromuscular junctionNMJby inhibiting acetylcholine breakdowncould be a potential therapy for SMA.

Pediatric UseSafety and effectiveness in pediatric patients have not been established.

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NOTEFor information on a diagnostic test for myasthenia gravisand for the evaluation and stabilization of therapyplease see product literature on Tensilonedrophonium chloride

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