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By 2012, france had suspended the use of actos due to the bladder cancer risk, and the governmental drug safety agency in canada also released a report that actos could have over two times the risk of bladder cancer for diabetes patients who were taking the potentially dangerous drug.

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Tabl 7. Tatmnt-mgnt Advs vnts Congstiv Hat ailu (CH) in Patints with NYHA Class II III Congstiv Hat ailu Tatd with ACTOS Glybuid.

Masu liv tsts pomptly in patints whpot symptoms that may indicat liv injuy, including atigu, anoxia, ight upp abdominal discomot, dak uin jaundic. In this clinical contxt, i th patint is ound thav abnomal liv tsts (ALT gat than 3 tims th upp limit th nc ang), ACTOS tatmnt should b intuptd and invstigation don tstablish th pobabl caus. ACTOS should not b statd in ths patints without anoth xplanation th liv tst abnomalitis.

Actos has a black box waning congstiv hat ailu, but th dug may alscaus oth sious sid cts, including bladd canc and liv ailu.

Th hav bn postmakting pots atal and non-atal hpatic ailu in patints taking ACTOS, although th pots contain insuicint inomation ncssay tstablish th pobabl caus. Th has bn nvidnc dug-inducd hpatotoxicity in th ACTOS contolld clinical tial databas tdat [s ADVS ACTIONS ].

Stop using pioglitazon and call you doctat onc i you hav any ths sious sid cts:

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be aware that women may be more likely than men to have bone fractures in their hand, upper arm or foot while taking actos.

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